Top 10 Best Stomach Supplements for Dogs in 2025: A Comprehensive Guide
Maintaining your dog’s digestive health is crucial for their overall well-being. Stomach supplements for dogs, such as probiotics, prebiotics, and digestive enzymes, can help alleviate common issues like diarrhea, gas, constipation, and upset stomachs while boosting immunity. In this comprehensive guide, we’ve curated the top 10 best-selling stomach supplements for dogs available on Amazon in 2025. Each product is designed to support your dog’s gut health, improve digestion, and enhance their quality of life. We’ll explore the features, benefits, and usage instructions for each supplement, along with tips to help you choose the right one for your furry friend. Let’s dive into the world of canine digestive health!
Why Choose Stomach Supplements for Dogs?
Dogs can experience a range of digestive issues, from occasional diarrhea and gas to chronic sensitivities and allergies. Stomach supplements, particularly those containing probiotics, prebiotics, fiber, and enzymes, help restore balance to the gut microbiome, promote healthy digestion, and support the immune system. These supplements are especially beneficial for dogs undergoing stress (e.g., travel or kenneling), recovering from antibiotics, or transitioning to a new diet. Whether you have a picky eater, a puppy, or a senior dog, the right supplement can make a significant difference. Our list highlights products that are vet-recommended, made with high-quality ingredients, and tailored to dogs of all breeds and sizes.
Top 10 Best-Selling Stomach Supplements for Dogs in 2025
We’ve researched and selected the top 10 best-selling stomach supplements for dogs on Amazon, focusing on quality, effectiveness, and customer satisfaction. Each product is designed to address specific digestive concerns while being easy to administer and palatable for dogs. Below, we detail each supplement, including its key features, benefits, and how to use it effectively.
Zesty Paws Probiotic for Dogs – Probiotics for Gut Flora, Digestive Health, Occasional Diarrhea & Bowel Support – Clinically Studied DE111 – Functional Dog Supplement Soft Chews for Pet Immune System
The Zesty Paws Probiotic for Dogs is a top-rated supplement designed to support your dog’s digestive and immune health. Featuring a base of pumpkin and papaya (rich in enzymes) and the clinically studied DE111 probiotic (Bacillus subtilis), these soft chews promote healthy gut flora and help with occasional diarrhea, gas, and bloating. The six-strain probiotic blend, including Lactobacillus acidophilus and L. plantarum, supports digestion and immunity for dogs of all sizes.
- Pumpkin and papaya base provides natural enzymes
- Clinically studied DE111 probiotic for digestive and immune support
- Six-strain probiotic blend to address diarrhea, gas, and bloating
- Supports gut flora for overall digestive health
- Tasty soft chews suitable for small, medium, and large breeds
How to Use: Administer the recommended number of chews daily based on your dog’s weight (check the packaging for dosage). Offer as a treat or mix with food. Store in a cool, dry place.
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Probiotics for Dogs with Prebiotics – Daily Chews for Digestion, Regularity, Diarrhea Relief, Plus Supports Immune System and Health – Natural Supplement and Treat Made in USA
These duck-flavored soft chews are a premium choice for supporting your dog’s digestive health. Made in a cGMP-certified facility in the USA, this supplement combines a patented probiotic strain with prebiotics to maintain a healthy GI tract, improve digestion, and support immunity. It’s ideal for dogs experiencing stress, diarrhea, or recovering from antibiotics, and it’s free of wheat, corn, and artificial ingredients.
- Patented probiotic strain for effective digestion support
- Made in the USA with rigorous quality testing
- Duck-flavored chews for easy administration
- Supports microbial balance during stress or antibiotic use
- 30-day Love-It Promise for customer satisfaction
How to Use: Give the recommended number of chews daily based on your dog’s weight. Serve as a treat or mix with food. Consult your veterinarian if your dog has specific dietary needs.
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Dog Probiotics Treats for Picky Eaters – Digestive Enzymes + Prebiotics – Chewable Fiber Supplement – Allergy, Diarrhea, Gas, Constipation, Upset Stomach Relief – Improve Digestion, Immunity
Designed for picky eaters, these chicken-flavored probiotic chews combine probiotics, prebiotics, fiber, and enzymes to address a range of digestive issues, including gas, diarrhea, constipation, and bad breath. Made in the USA with no soy, corn, dairy, or sugar, this supplement supports digestion and immunity for dogs of all breeds and ages, offering up to a 3-month supply per jar.
- Chicken-flavored chews appeal to picky eaters
- Supports digestion and allergy relief
- 120 chews for up to 3 months of supply
- No soy, corn, dairy, or artificial flavors
- Suitable for all breeds and ages
How to Use: Administer the recommended number of chews daily based on your dog’s size. Serve as a treat or crumble into food. Store in a cool, dry place.
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Veterinarian Strength Advanced Probiotics, Healthy Enzymes and PB6 Probiotic Supplement For Your Dogs Stomach, Intestine, Digestion and GI Tract health, Made by NaturVet, 120 Soft Chews
NaturVet’s Veterinarian Strength Advanced Probiotics offer a powerful blend of probiotics and enzymes to optimize nutrient absorption and support GI health. Featuring PB6 technology, this supplement ensures beneficial bacteria reach the entire GI tract. Wheat-free and made in the USA, these tasty soft chews are vet-formulated and backed by a 100% satisfaction guarantee.
- PB6 probiotic technology for complete GI support
- Enzymes enhance nutrient absorption
- Wheat-free and vet-formulated
- Made in the USA in a cGMP-compliant facility
- 100% satisfaction guarantee
How to Use: Administer the recommended number of chews daily based on your dog’s weight. Offer as a treat or mix with food. Consult your vet for long-term use.
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The Honest Kitchen Herbal Digestive Supplement Pet food for Cats and Dog
The Honest Kitchen Herbal Digestive Supplement is a human-grade, NASC-certified product designed to soothe and protect the GI tract. Ideal for dogs and cats with occasional loose stools due to stress or dietary changes, this supplement is free of preservatives, GMOs, corn, wheat, and soy. Made in the USA, it’s easy to mix with food or water.
- Human-grade ingredients for high quality
- NASC-certified for safety and efficacy
- Herbal formula soothes the GI tract
- No preservatives, GMOs, corn, wheat, or soy
- Easy to mix with food or water
How to Use: Mix the recommended amount of dry mix with water to form a paste. Combine with your dog’s food or a topper. Follow dosage instructions based on weight.
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Perfect Poop Digestion & General Health Supplement for Dogs: Fiber, Prebiotics, Probiotics & Enzymes Relieve Digestive Conditions, Optimize Stool, and Improve Health (Cheddar Cheese, 12.8 oz)
The Perfect Poop Digestion Supplement combines fiber, prebiotics, probiotics, and enzymes in a cheddar cheese-flavored formula. It addresses diarrhea, constipation, bloating, and bad breath while improving nutrient absorption and overall health. Made with natural, non-GMO ingredients like miscanthus grass and pumpkin powder, it’s a comprehensive solution for gut health.
- 4-in-1 formula with fiber, prebiotics, probiotics, and enzymes
- Reduces diarrhea, constipation, and stool odor
- Natural, non-GMO ingredients like miscanthus grass and pumpkin
- Improves nutrient absorption and immune health
- One bag lasts a 50 lb dog over a month
How to Use: Mix the recommended serving size with your dog’s food or serve as a treat. Dosage varies by weight. Store in a cool, dry place.
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Probiotic for Dogs with Natural Digestive Enzymes. A Prebiotics + Digestive Enzyme product for dogs + Pumpkin. 120 Servings. Diarrhea & Upset Stomach Relief + Gas, Constipation, and Allergy Relief.
This vet-recommended supplement combines five probiotic strains, digestive enzymes, and pumpkin to provide immediate relief from digestive discomfort. With over 3 billion CFUs per serving, it supports gut health, reduces gas and constipation, and helps with allergies. Made with organic ingredients, it’s suitable for dogs of all ages and sizes.
- Five probiotic strains with over 3 billion CFUs
- Pumpkin and enzymes for digestive relief
- Organic, vet-recommended formula
- 120 servings for long-term use
- Suitable for all breeds and ages
How to Use: Administer the recommended dosage daily based on your dog’s weight. Mix with food or water for easy administration. Store in a cool, dry place.
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Dog Probiotics Chews – Gas, Diarrhea, Allergy, Constipation, Upset Stomach Relief, with Digestive Enzymes + Prebiotics – Chewable Fiber Supplement – Improve Digestion, Immunity – Made in USA – 120 Ct
Bark&Spark’s Dog Probiotics Chews offer advanced digestion support with a blend of probiotics, prebiotics, fiber, and enzymes. These chicken-flavored chews address gas, diarrhea, and allergies while promoting a healthy gut microbiome. Made in the USA with human-grade ingredients, this supplement provides up to a 4-month supply for small to large dogs.
- Addresses gas, diarrhea, constipation, and allergies
- Chicken-flavored chews for easy administration
- 120 chews for up to 4 months of supply
- Made in the USA with human-grade ingredients
- No sugar, dairy, or corn
How to Use: Give the recommended number of chews daily based on your dog’s size. Serve as a treat or mix with food. Store in a cool, dry place.
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Vet’s Best Gas Busters Dog Supplements | Gas, Bloating, Constipation Relief and Digestion Aid for Dogs | 90 Chewable Tablets
Vet’s Best Gas Busters are vet-formulated chewable tablets designed to relieve gas, bloating, and constipation. Featuring a blend of parsley, slippery elm bark, ginger root, and probiotics, this supplement promotes a healthy gut microbiome and supports digestion. It’s ideal for dogs with occasional digestive discomfort.
- Relieves gas, bloating, and constipation
- Vet-formulated with parsley, slippery elm, and ginger
- Probiotic blend for a healthy gut microbiome
- Chewable tablets for easy administration
- 90 tablets per bottle
How to Use: Administer twice daily as directed based on your dog’s weight. Offer as a treat or crush and mix with food. Consult your veterinarian for long-term use.
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Tummy – Natural, Electrolyte, Odorless Pet Supplement That Relieves Stomach Pain and Nausea (Dropper, 1 Ounce)
The Tummy Natural Pet Supplement is an odorless, electrolyte-rich dropper formula designed to relieve stomach pain and nausea. Made with human-grade vitamins and minerals, it’s ideal for dogs experiencing digestive upset. For best results, it can be used alongside other Epic products like Repair, Digest, and Vitality.
- Relieves stomach pain and nausea
- Odorless, human-grade formula with electrolytes
- Easy-to-use dropper for precise dosing
- Complements other Epic supplements
- Suitable for dogs and cats
How to Use: Add the recommended number of drops to your dog’s food or water at each meal. Follow dosage instructions based on weight. Store in a cool, dry place.
Buy on AmazonTips for Choosing the Best Stomach Supplement for Your Dog
Selecting the right stomach supplement for your dog involves considering several factors to ensure effectiveness, safety, and ease of use. Here are some tips to guide your decision:
- Ingredients: Look for high-quality, natural ingredients like probiotics, prebiotics, fiber, and enzymes. Avoid supplements with artificial flavors, corn, wheat, or soy if your dog has sensitivities.
- Form: Choose a form that suits your dog’s preferences—chews for picky eaters, powders for mixing with food, or droppers for precise dosing.
- Purpose: Identify your dog’s specific needs, such as diarrhea relief, gas reduction, or general gut health, and select a supplement tailored to those issues.
- Vet Approval: Opt for vet-formulated or vet-recommended products, especially for dogs with chronic conditions or those on medication.
- Quality Standards: Choose supplements made in the USA in cGMP-compliant facilities or certified by NASC for safety and quality.
- Ease of Administration: Select palatable options like flavored chews to make daily supplementation easier.
- Brand Reputation: Trust brands like Zesty Paws, NaturVet, or Vet’s Best, which offer satisfaction guarantees and rigorous quality testing.
How to Use Stomach Supplements Effectively
To maximize the benefits of stomach supplements for your dog, follow these steps:
- Consult Your Veterinarian: Before starting any supplement, consult your vet to ensure it’s suitable for your dog’s health needs, especially if they’re on medication.
- Follow Dosage Instructions: Adhere to the recommended dosage based on your dog’s weight and size. Overdosing can cause adverse effects.
- Introduce Gradually: Start with a smaller dose to help your dog adjust, especially if they’re new to supplements. Monitor for any adverse reactions.
- Administer Consistently: For best results, give the supplement daily as directed. Incorporate it into your dog’s routine, whether as a treat or mixed with food.
- Monitor Progress: Track your dog’s digestive health over a few weeks to assess the supplement’s effectiveness. Note improvements in stool quality, energy, or appetite.
- Store Properly: Keep supplements in a cool, dry place to maintain potency. Follow storage instructions on the packaging.
Conclusion
Supporting your dog’s digestive health is key to their overall happiness and vitality. Our top 10 best-selling stomach supplements for dogs in 2025, including Zesty Paws Probiotic, NaturVet Advanced Probiotics, and The Honest Kitchen Herbal Supplement, offer effective solutions for diarrhea, gas, constipation, and more. By choosing a high-quality supplement tailored to your dog’s needs, you can improve their gut health and quality of life. Explore these products on Amazon to make an informed purchase, and visit Best Family Pets for more pet care tips and product recommendations. Keep your furry friend healthy and happy!
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